REGULATION OF ERBB2 RECEPTOR STATUS BY THE PROTEASOMAL DUB POH1.

Regulation of ErbB2 receptor status by the proteasomal DUB POH1.

Understanding the factors, which control ErbB2 and EGF receptor (EGFR) status in cells is likely to inform future therapeutic approaches directed at these potent oncogenes.ErbB2 is resistant to stimulus-induced degradation and high levels of over-expression can inhibit EGF receptor down-regulation.We now show that for HeLa cells expressing similar

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Novel Prescribed Performance Control Scheme for Flexible Hypersonic Flight Vehicles with Nonaffine Dynamics and Neural Approximation

This study develops a novel neural-approximation-based prescribed performance controller click here for flexible hypersonic flight vehicles (HFVs).Firstly, a new prescribed performance mechanism is exploited, which develops new performance functions guaranteeing velocity and altitude tracking errors with small overshoots.Compared with the existing

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Benign and tumor parenchyma metabolomic profiles affect compensatory renal growth in renal cell carcinoma surgical patients.

BACKGROUND AND OBJECTIVES:Pre-operative kidney volume is an independent predictor of glomerular tillman 750m filtration rate in renal cell carcinoma patients.Compensatory renal growth (CRG) can ensue prior to nephrectomy in parallel to tumor growth and benign parenchyma loss.We aimed to test whether renal metabolite abundances significantly associa

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